TUF's Research Scholars

The Urology Foundation is delighted to announce that we awarded five TUF Innovation & Research Awards in 2021. 

The projects cover kidney stones, small renal tumours, bladder cancer, urinary incontinence and pelvic mesh.

 

Research Scholars 2021

Sarah Howles - Nuffield Department of Surgical Sciences, University of Oxford

Defining the role of biased calcium-sensing receptor signalling in kidney stone disease

Abstract:

Biased signalling via the calcium-sensing receptor (CaSR) may be a common cause of kidney stone disease; this project aims to fully elucidate the effects of kidney-stone associated genetic variants on CaSR-signalling and identify drugs that have the potential to be innovative therapies for kidney stone prevention.

 

Michael Hughes - University of Surrey

Mail-In canceR dIagnosis and Analysis by Dielectrophoresis - Bladder Cancer (MIRIAD-BC)

Abstract:

We have previously demonstrated that electrical analysis of cells in urine allows diagnosis of bladder cancer; in this study we will develop this technique, optimising sample collection and analysis, identifying methods of tumour grading, and quantify how long samples can last before processing, ahead of a subsequent clinical trial.

 

Michael Jeffryes - Guy's & St Thomas' NHS Trust

Development and validation of Intra-urethral intra-operative pressureDevelopment and validation of Intra-urethral intra-operative pressuremeasurement system for optimal sling tensioning

Abstract:

This project aims to develop and validate a system that can be used to measure pressure along the urethra (waterpipe/bladder outlet) during surgery to treat stress urinary incontinence (SUI, leakage of urine during exercise, cough, sneeze or strain).

 

Nikesh Thirulchelvam - Addenbrookes Hospital, Cambridge University NHS Trust

Promoting an understanding of pelvic mesh complications: Development and validation of a condition-specific Patient Reported Outcome Measure

Abstract:

The aim of this project is to develop and validate a Patient Reported Outcome Measure (PROM) that can be used to assess pain related to pelvic mesh implants, including following mesh removal procedures.

 

Hannah Warren - Royal Free Hospital / University College London

Sestamibi Kidney for the Assessment of renal Neoplasms (SKAN)

Abstract:

This project aims to evaluate existing and novel diagnostic imaging techniques in the assessment of small renal tumours, with a view to reducing unnecessary invasive diagnostics and management in patients with benign disease.

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